C

 

Cherubism

Kalıtsal - AD

İlk bulgular 2-5 yaşlarında

Çenelere (birinde/ikisinde) bilateral, simetrik genişleme

Altçenede koronoidlere ve kondillere dek etkilenme

Büyüyen üstçenenin göz kapaklarını aşağı çekmesi (cherubic look)

Azıların eksikliği

Dişlerin erken yitirilmesi (süt)

Maloklüzyon

Gingival fibromatozis

Puberteyle birlikte gerilemeye başlayan ağrısız oluşumlar

Radyolojide bilateral multiloküler litik lezyonlar

Mikroskopide dev hücreleri içeren fibroblastik aktivite

Submandibular lenfadenopati

Optik nöropati

 

• De Lange J, Van den Akker HP. Clinical and radiological features of central giant-cell lesions of the jaw. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontology, 99:464–470, 2005

• Carvalho Silva E, Carvalho Silva GC, Vieira TC. Cherubism: clinicoradiographic features, treatment, and long-term follow-up of 8 cases. Journal of Oral & Maxillofacial Surgery, 65(3):517-522, 2007

• Roginsky VV, Ivanov AL, Ovtchinnikov A, Khonari RH. Familial cherubism: the experience of the Moscow central institute for stomatology and maxillo-facial surgery. International Journal of Oral & Maxillofacial Surgery, 38:218–223, 2009

• Haritha A, Jayakumar A. Syndromes as they relate to periodontal disease. Periodontology 2000, 56:65–86, 2011

• Dyasanoor S, Naik S. Clinicoradiologic features of cherubism: a case report and literatüre review. General Dentistry, 62(5):e12-15, 2014

• Tsodoulos S, Ilia A, Antoniades K, Angelopoulos C. Cherubism: a case report of a three-generation inheritance and literature review. Journal of Oral & Maxillofacial Surgery, 72(2):405.e1-9, 2014

• Jiao Y, Zhou M, Yang Y, Zhou J, Duan X. Cherubism misdiagnosed as giant cell tumor: a case report and review of the literature. International Journal of Clinical & Experimental Medicine, 8(3):4656-4663, 2015