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Multipl endokrin neoplazi sendromu 1

MEN1; Wermer sendromu

Kalıtsal - AD  TABLO

Çoğu endokrin kökenli tümörler

Paratiroid adenomu (hiperkalsemi, metastatik kalsifikasyonlar)

Pankreas adacık tümörü (gastrinoma, glukagonoma, insülinoma, anemi, venöz tromboz, diyare)

Gastrinoma tümörlerinde “Zollinger-Ellison sendromu”

Glukagonoma’da deri döküntüleri

Hipofiz tümörü (prolaktioma; kadınlarda oligomenore/amenore, galaktore, erkeklerde cinsel disfonksiyon ve jinekomasti; büyüme hormonu artışında akromegali; ACTH üretiminde Cushing sendromu)

Adrenal korteks tümörü (hiperkortizolizm, hiperaldosteronizm)

Karsinoid (hormon üretmeyen tümörler)

Endokrin niteliği olmayan tümörler (yüz derisinde angiofibromalar, deride lipoma, meningioma, ependimoma, leiomyomalar)

Gingival hiperplazi (nodüler)

Glossit

Café-au-lait

Serpilmiş vitiligo lekeleri

Hiperglisemi

Hiperkalsüri

Ürolityazis

Akromegali

Aklordihri

Anemi

Bkz Zollinger-Ellison sendromu

 

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