Oligodonti-kolorektal karsinom sendromu

Kalıtsal - AD

Saçlar seyrek

Kaşlar seyrek

Oligodonti (sürekli dişlerde)

Meme kanseri (bazı genç hastalarda)

Kolorektal karsinom (genç yaşlarda)

GİS polipleri

 

  • Lammi L, Arte S, Somer M, et al. Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. American Journal of Human Genetics, 74: 1043-1050, 2004

  • Bergendal B, Klar J, Stecksen-Blicks C, et al. Isolated oligodontia associated with mutations in EDARADD, AXIN2, MSX1, and PAX9 genes. American Journal of Medical Genetics, 155A: 1616-1622, 2011

  • Marvin ML, Mazzoni SM, Herron CM, et al. AXIN2-associated autosomal dominant ectodermal dysplasia and neoplastic syndrome. American Journal of Medical Genetics, 155A: 898-902, 2011