OMPP sendromu (osteomyelitis-periostitis-pustulosis)

Kalıtsal - AR

Ülserli stomatit

Kosta anomalileri

Hepatosplenomegali

Periostta sıyrılmalar

Multifokal/steril osteolizis

Eklemlerde şişme/ağrı

Deride çok sayıda püstül (pustular psoriasis)

Tırnaklarda psöriazise özgü bulgular

ESR yüksek

C-RP yüksek

 

  • Ivker RA, Grin-Jorgensen CM, Vega VK, et al. Infantile generalized pustular psoriasis associated with lytic lesions of the bone. Pediatric Dermatology, 10: 277-282, 1993

  • Aksentijevich I, Masters SL, Ferguson PJ, et al. An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. New England Journal of Medicine, 360: 2426-2437, 2009

  • Reddy, S., Jia, S., Geoffrey, R., Lorier, R., Suchi, M., Broeckel, U., Hessner, M. J., Verbsky, J. An autoinflammatory disease due to homozygous deletion of the IL1RN locus. New England Journal of Medicine, 360: 2438-2444, 2009