Peutz-Jeghers sendromu
Kalıtsal - AD
Burun polipleri
Dudaklarda koyu renkli çiller
Yanak mukozasında koyu renkli çiller
Bronş polipleri
Sertoli hücreli tümör ve jinekomasti
Erkek çocuklarında erken puberte
Safra yolları polipleri
Mide-rektum arasında hamartomatöz polipler
GİS poliplerinde ağrı
İleus (intussusception)
Ovaryum kistleri
Üreter papillomları
Mesane papillomları
El derisinde hiperpigmante çiller
Café-au-lait
Demir eksikliği anemisi
Tümör riski: karsinom (GİS, meme, tiroid, akciğer, pankreas, uterus), ovaryum ve testis tümörleri
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Brinster DR, Raper SE. Synchronous colon and pancreatic cancers in a patient with Peutz-Jeghers syndrome: report of a case and review of the literature. Surgery, 135(3):352-354, 2004
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Hearle N, Schumacher V, Menko FH, et al. Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. Clinical Cancer Research, 12(10):3209-3215, 2006
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Kopacova M, Tacheci I, Rejchrt S, Bures J. Peutz-Jeghers syndrome: diagnostic and therapeutic approach. World Journal of Gastroenterology, 15(43):5397-5408, 2009
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Beggs AD, Latchford AR, Vasen HF, et al. Peutz-Jeghers syndrome: a systematic review and recommendations for management. Gut, 59:975–986, 2010
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van Lier MG, Wagner A, Mathus-Vliegen EMH, et al. High cancer risk in Peutz-Jeghers syndrome: a systematic review and surveillance recommendations. The American Journal of Gastroenterology, 105:1258–1264, 2010