S

 

Sezary sendromu

40 yaşından büyüklerde

Deri yerleşimli T-cell lenfoma (mycosis fungoides)

Eritroderma

Güçlü kaşıntı

Lenfadenopati

Saç ve kıllarda dökülmeler

Tırnak distrofileri

Anormal lenfositler (kan)

Hepatosplenomegali

Lösemi riski

 

  • Hwang ST, Janik JE, Jaffe ES, Wilson WH. Mycosis fungoides and Sézary syndrome. Lancet, 371(9616):945-957, 2008

  • Campbell JJ, Clark RA, Watanabe R, Kupper TS. Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors. Blood, 5;116(5):767-771, 2010

  • Wang L, Ni X, Covington KR, et al. Genomic profiling of Sezary syndrome identifies alterations of key T cell signaling and differentiation genes. Nature Genetics, 47: 1426-2434, 2015

  • Foss FM, Girardi M. Mycosis Fungoides and Sezary Syndrome. Hematology/Oncology Clinics of North America, 31(2):297-315, 2017

  • Thompson AK, Killian JM, Weaver AL, et al. Sézary syndrome without erythroderma: A review of 16 cases at Mayo Clinic. Journal of the American Academy of Dermatology, 76(4):683-688, 2017